Speech-language pathologists often struggle with complex and treatment resistant speech disorders of children on their caseloads, specifically Childhood Apraxia of Speech (CAS). CAS will be described in detail in order to set the pace for this course. CAS assessment methods and treatment approaches based on evidence based practice, including ASHA guidelines will be presented. Questions will be answered related to diagnosis of very young children, to the number of minutes and types of therapy provided by school SLPs, to functional communication, to how to work on residual issues with adolescents. SLPs will gain information on differential diagnosis of CAS as well as the importance of dynamic assessment for some children with CAS. This seminar will also address CAS secondary to other conditions such as autism and Down Syndrome. Real-life complex cases will be discussed from videos. Comparison of motor performance and motor learning related to CAS therapy will be explained. Since children with CAS have difficulties at both segmental and suprasegmental levels, a variety of therapies related to both issues will be addressed. Many older children require work on residual issues, such as vowels, multisyllabic words, and speech intelligibility in conversation. Treatment techniques for these issues will be described. The severity of CAS, the necessity of long-term therapy, and overall prognosis will also be examined. CAS is a dynamic disorder and the assessment and treatment of these clients must also be dynamic in nature.